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Volume 1, Issue 3 (July 2022)
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Identification of Pathogenic Fungi in Renal Transplant Patients by Conventional and Molecular Methods
Faheema Jabbar
 Tropical Biological Research Unit, College of Science, University of Baghdad - Iraq
 faheemajabbar@uobaghdad.edu.iq
 Corresponding Author
Azhar A.Al-Attraqchi
 Department of Medical Microbiology, College of Medicine, Al-Nahrain University, Baghdad - Iraq
Dina Nabeel Alkhayyat
 Kidney Disease and Transplantation Center / Baghdad Medical City, Baghdad - Iraq
ISSN(e): 2790-296X
ISSN(p): 2957-5826
About the Journal
Editor in Chief:
Prof. Dr. Emad Al-Mulla
 
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BCS is published quarterly
 
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Opportunistic fungal infections due to the immune- compromised status of renal transplant patients are related to high rates of morbidity and mortality regardless of their minor incidence. Delayed in identification of invasive fungal infections (IFIs), will lead to delayed treatment and results in high mortality in those populations. The study aimed to assess the frequency of invasive fungal infection in kidney transplant recipients by conventional and molecular methods. This study included 100 kidney transplant recipients (KTR) (75 males, and 25 females), collected from the Centre of Kidney Diseases and Transplantation in the Medical City of Baghdad. Blood samples were collected during the period from June 2018 to April 2019. Twenty one out of 100 renal-transplanted patients were infected with pathogenic fungi, four of the patients were females and 17 were males. There is an observation of a high incidence of fungemia in patients with the abnormal value of blood urea according to PCR and culture results. Referring to fungal isolates the most prevalent was Saccharomyces cerevisiae, which account for 19 isolates out of 21 the other two isolates were Zygosaccharomyces rouxii and Aspergillus flavus. The results of the current study show significant correlation between PCR and culture methods at (P<0.0009).

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Keywords: Conventional Methods, Fungal Infection, ITS2, PCR, Renal Transplant

How to Cite:
Jabbar, F., A.Al-Attraqchi, A., & Alkhayyat, D. N. (2022). Identification of Pathogenic Fungi in Renal Transplant Patients by Conventional and Molecular Methods. Biomedicine and Chemical Sciences, 1(3), 126–131. https://doi.org/10.48112/bcs.v1i3.198
 
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© 2022 Biomedicine and Chemical Sciences published by International Research and Publishing Academy (iRAPA) - Pakistan Co-published by Al-Furat Al-Awsat Technical University - Iraq
 
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