Design and Synthesis Ligands Tetradents Substituted with Halogenes in α- Position and Conjugation with Riboflavin (Bioconjugates) Conjugate ligands Type TPA’s with Flavonoids as un Electron Mediator
In this article, we describe the process of binding riboflavin to a simple tetradents ligand substituted in α- position from TPAs types, by reacting bromotetraacetate riboflavin with α- substituted TPA with one of the pyridine rings by nitrile group and the two other pyridine rings by halogen atoms. This type…